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GTP-BINDING PROTEIN ALPHA SUBUNITS
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DeCS
Descriptor
English
:
GTP-Binding Protein alpha Subunits
Descriptor
Spanish
:
Subunidades alfa de la Proteína de Unión a GTP
Descriptor
Portuguese
:
Subunidades alfa de Proteína de Ligação a GTP
Tree Number:
D08.811.277.040.330.300.200.100
D12.644.360.375.100
D12.776.157.325.332.100
D12.776.476.375.100
D12.776.543.325.100
Definition
English
:
The GTPase-containing subunits of
heterotrimeric GTP-binding proteins
. When dissociated from the heterotrimeric complex these subunits interact with a variety of
second messenger systems
.
Hydrolysis
of GTP by the inherent GTPase activity of the subunit causes it to revert to its inactive (heterotrimeric) form. The
GTP-Binding protein alpha subunits
are grouped into families according to the type of action they have on
second messenger systems.
History Note
English
:
2004; use HETEROTRIMERIC GTP-BINDING PROTEINS 2001-2003
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
38130
Unique Identifier:
D044385
Occurrence in VHL
:
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